Development and testing of an automated microscopy complex

Медовый В.С., Пятницкий А.М., Соколинский Б.З., Маркеллов В.В., Федорова Д.С., Федоров И.В. Разработка и испытание автоматизированного комплекса микроскопии // Оптический журнал. 2011. Т. 78. № 1. С. 66–73.

Medoviy V.S., Pyatnitskiy, Sokolinskiy B.Z., Markellov V.V., Fedorova D.S., Fedorov I.V. Development and testing of an automated microscopy complex [in Russian] // Opticheskii Zhurnal. 2011. V. 78. № 1. P. 66–73.

V. S. Medovyĭ, A. M. Pyatnitskiĭ, B. Z. Sokolinskiĭ, V. V. Markellov, D. S. Fedorova, and I. V. Fedorov, "Development and testing of an automated microscopy complex," Journal of Optical Technology. 78(1), 50-56 (2011). https://doi.org/10.1364/JOT.78.000050

The high variability of the specimens creates problems in the formation of both a representative model of the ambient medium and stable algorithms for the automatic microscopic analysis of biomaterials. When the MECOS-C2 analyzer is being developed and maintained, the technology of reference virtual slides formed with the participation of the users and available during operation from laboratories in the service center is used to obtain a model of the ambient medium. The structure of the MECOS-C2, adjusted to use virtual slides, makes it possible to largely automate the development of new versions of the software, taking into account the data on the ambient medium. Another key principle of the development is to use robust analysis algorithms adapted to a given specimen. The combination of these principles made it possible to create the medical-class MECOS-C2 automatic analyzer suitable for analyzing blood smears in a commercial laboratory.