УДК: 616.314-72, 535-1, 535.8
Experimental studies of the possibilities of diagnosing caries in the solid tissues of a tooth by means of terahertz radiation
Full text «Opticheskii Zhurnal»
Full text on elibrary.ru
Publication in Journal of Optical Technology
Смирнов С.В., Грачёв Я.В., Цыпкин А.Н., Беспалов В.Г. Экспериментальные исследования возможностей диагностирования кариеса в твердых тканях зуба с помощью терагерцового излучения // Оптический журнал. 2014. Т. 81. № 8. С. 58–62.
Smirnov S.V., Grachev Ya.V., Tsypkin A.N., Bespalov V.G. Experimental studies of the possibilities of diagnosing caries in the solid tissues of a tooth by means of terahertz radiation [in Russian] // Opticheskii Zhurnal. 2014. V. 81. № 8. P. 58–62.
S. V. Smirnov, Ya. V. Grachev, A. N. Tsypkin, and V. G. Bespalov, "Experimental studies of the possibilities of diagnosing caries in the solid tissues of a tooth by means of terahertz radiation," Journal of Optical Technology. 81(8), 464-467 (2014). https://doi.org/10.1364/JOT.81.000464
Spectroscopic and tomographic studies on the solid tissues of a human tooth have been carried out in the terahertz (THz) frequency range. It is experimentally shown that, in samples of dental tissue damaged by caries, the absorption lines of water in the THz region have higher intensity by comparison with the intensity of healthy tissue. The radiation intensity in the THz frequency range reflected from samples of human dental enamel damaged by caries in this case is smaller by a factor of 2.2 and from samples of dentine is smaller by a factor of 4.5 by comparison with samples of healthy tissue.
terahertz radiation, spectroscopy, tomography
Acknowledgements:This work was carried out with state financial support of the leading universities of the Russian Federation (Subsidy 074-U01).
OCIS codes: 170.4580, 170.1850, 170.0110, 170.6280, 170.4500, 170.6795
References:1. B. B. Hu and M. C. Nuss, “Imaging with terahertz waves,” Opt. Lett. 20, 1716 (1995).
2. X.-C. Zhang and J. Xu, Introduction to THz Wave Photonics (Springer Science + Business Media, New York, 2010).
3. D. Arnone, C. Ciesla, and P. Michael, “Terahertz imaging comes into view,” Phys. World 4, 35 (2000).
4. V. P. Wallace, A. J. Fitzgerald, and S. Shankar, “Terahertz pulsed imaging of basal cell carcinoma ex vivo and in vivo,” Br. J. Dermatol. 151, 424 (2004).
5. A. G. Markelz, A. Roitberg, and E. J. Heilweil, “Pulsed terahertz spectroscopy of DNA, bovine serum albumin and collagen between 0.1 and 2.0 THz,” Chem. Phys. Lett. 320, 42 (2000).
6. D. Polley, A. Patra, and R. K. Mitra, “Dielectric relaxation of the extended hydration sheath of DNA in the THz frequency region,” Chem. Phys. Lett. 586, 143 (2013).
7. R. M. Woodward, V. P. Wallace, D. D. Arnone, E. H. Linfield, and M. Pepper, “Terahertz pulsed imaging of skin cancer in the time and frequency domain,” J. Biol. Phys. 29, 257 (2003).
8. D. M. Mittleman, R. H. Jacobsen, and M. C. Nuss, “T-ray imaging,” IEEE J. Sel. Top. Quantum Electron. 2, 679 (1996).
9. D. A. Crawley, C. Longbottom, B. E. Cole, C. M. Ciesla, D. Arnone, V. P. Wallace, and M. Pepper, “Terahertz pulse imaging: a pilot study of potential applications in dentistry,” Caries Res. 37, 352 (2003).
10. Z. D. Taylor, R. S. Singh, D. B. Bennett, P. Tewari, C. P. Kealey, N. Bajwa, M. O. Culjat, A. Stojadinovic, H. Lee, J. Hubschman, E. R. Brown, and W. S. Grundfest, “THz medical imaging: in vivo hydration sensing,” IEEE Trans. Terahertz Sci. Technol. 1, 201 (2011).
11. M. Schwerdtfeger, S. Lippert, M. Koch, A. Berg, S. Katletz, and K. Wiesauer, “Terahertz time-domain spectroscopy for monitoring the curing of dental composites,” Biomed. Opt. Express 3, 2842 (2012).
12. C. M. Ciesla, D. D. Arnone, A. Corchia, D. A. Crawley, C. Longbottom, E. H. Linfield, and M. Pepper, “Biomedical applications of terahertz pulse imaging,” Proc. SPIE 3934, 73 (2000).
13. D. Crawley, C. Longbottom, V. P. Wallace, B. Cole, D. Arnone, and M. Pepper, “Three-dimensional terahertz pulse imaging of dental tissue,” J. Biomed. Opt. 8, 303 (2003).
14. M. Schirmer, M. Fujio, M. Minami, J. Miura, T. Araki, and T. Yasui, “Biomedical applications of a real-time terahertz color scanner,” Biomed. Opt. Express 1, 354 (2010).
15. E. Pickwell and V. P. Wallace, “Biomedical applications of terahertz technology,” J. Phys. D 39, No. 17, R301 (2006).
16. M. Addy, G. Embery, W. Edgar, and R. Orchardson, Tooth Wear and Sensitivity (Martin Dunitz Ltd., 2000).
17. A. Milosevic, P. Young, and M. Lennon, “The prevalence of tooth wear in 14-year-old school children in Liverpool,” Community Dent. Health 11, 83 (1993).
18. A. Millward, L. Shaw, and A. Smith, “Continuous intra-oral pH monitoring after consumption of acidic beverages,” J. Dent. Res. 73, abstract no. 389 (1994).
19. M. S. Kulya, Ya. V. Grachev, and V. G. Bespalov, “Obtaining topograms using a pulsed terahertz refractometer,” Nanosist. Fiz. Khim. Mat. 3, No. 5, 33 (2012).
20. D. M. Mittleman, S. Hunsche, L. Boivin, and M. C. Nuss, “T-ray tomography,” Opt. Lett. 22, 904 (1997).