УДК: 615.831, 535.217, 544.525.2, 615.277.3, 616-006

Study of the photophysical properties of a water-soluble photosensitizer of porphyrin nature—dimegin

Dadeko, A.V., Muravieva, T.D., Starodubtsev, A.M., Belousova, I.M.

Publication in Journal of Optical Technology

For Russian citation (Opticheskii Zhurnal):

Дадеко А.В., Муравьева Т.Д., Стародубцев А.М., Белоусова И.М. Изучение фотофизических свойств водорастворимого фотосенсибилизатора порфириновой природы - димегина // Оптический журнал. 2016. Т. 83. № 3. С. 71–75.

Dadeko A.V., Muravieva T.D., Starodubtsev A.M., Belousova I.M. Study of the photophysical properties of a water-soluble photosensitizer of porphyrin nature—dimegin [in Russian] // Opticheskii Zhurnal. 2016. V. 83. № 3. P. 71–75.

For citation (Journal of Optical Technology):

A. V. Dadeko, T. D. Murav’eva, A. M. Starodubtsev, and I. M. Belousova, "Study of the photophysical properties of a water-soluble photosensitizer of porphyrin nature—dimegin," Journal of Optical Technology. 83(3), 193-196 (2016). https://doi.org/10.1364/JOT.83.000193

Abstract:

A study has been carried out to compare the photophysical properties of a water-soluble photosensitizer of porphyrin nature (dimegin) with photosensitizers currently used in medical practice (photoditazin and radachlorin). Results are given for an investigation of the singlet-oxygen generation efficiency by the photosensitizers when they are irradiated by an LED array (radiation wavelength 395–405 nm). The luminescence spectra of the photosensitizers irradiated by an LED (wavelength 465 nm) were investigated, and it is pointed out that dimegin has higher luminescence intensity than photoditazin and radachlorin. A study was carried out of how the block copolymer Pluronic F-127 in a complex with dimegin affects the capability of the latter to generate singlet oxygen.

Keywords:

photosensitizer, singlet oxygen, luminescence, Soret peak, Pluronic, tryptophan, dimegin

Acknowledgements:

This research was carried out under a special commission of the Federal Medical and Biological Agency of Russia, as well as with the State Financial Support of the Leading Universities of the Russian Federation (Subsidy 074-U01).

OCIS codes: 170.0170, 170.5180, 000.1430, 170.6280, 300.0300, 300.1030, 300.6170, 300.6550

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