УДК: 544.164, 543.422.3, 543.426, 547.7, 547.6, 577.323

Investigation of mechanisms of change in spectral properties during interaction of benzazole, indole, and phenanthridium compounds with DNA

Publication in Journal of Optical Technology

For Russian citation (Opticheskii Zhurnal):

Сибирцев В.С. Исследование механизмов изменения спектральных свойств при взаимодействии с днк соединений бензазольного, индольного и фенантридиумного рядов // Оптический журнал. 2017. Т. 84. № 5. С. 13–21.

Sibirtsev V.S. Investigation of mechanisms of change in spectral properties during interaction of benzazole, indole, and phenanthridium compounds with DNA [in Russian] // Opticheskii Zhurnal. 2017. V. 84. № 5. P. 13–21.

For citation (Journal of Optical Technology):

V. S. Sibirtsev, "Investigation of mechanisms of change in spectral properties during interaction of benzazole, indole, and phenanthridium compounds with DNA," Journal of Optical Technology. 84(5), 294-301 (2017). https://doi.org/10.1364/JOT.84.000294

Abstract:

The absorption and fluorescence spectral data for 16 synthetic compounds of the indole, benzazole, and phenanthridium series in various media and in the presence of various amounts of deoxyribonucleic acid (DNA) are presented. The main features of a generalized model that makes it possible to adequately explain the changes in the spectral properties of such compounds as a function of their chemical structure, the nature of their interaction with the substrate, the properties of the measurement medium, etc., and to design new DNA-specific fluorophores with predetermined properties are provided.

Keywords:

DNA fluorescence analysis, DNA fluorophores, benzazole, indole

OCIS codes: 170.4580, 170.1530, 170.6280, 300.6390, 300.6280, 300.6550, 300.1030

References:

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