УДК: 535.372, 615.471, 519.245

How the melanin concentration in the skin affects the fluorescence-spectroscopy signal formation

Publication in Journal of Optical Technology

For Russian citation (Opticheskii Zhurnal):

Дрёмин В.В., Дунаев А.В. Влияние содержания меланина в коже на формирование сигнала флуоресцентной спектроскопии // Оптический журнал. 2016. Т. 83. № 1. С. 57–64.

Dryomin V.V., Dunaev A.V. How the melanin concentration in the skin affects the fluorescence-spectroscopy signal formation [in Russian] // Opticheskii Zhurnal. 2016. V. 83. № 1. P. 57–64.

For citation (Journal of Optical Technology):

V. V. Dremin and A. V. Dunaev, "How the melanin concentration in the skin affects the fluorescence-spectroscopy signal formation," Journal of Optical Technology. 83(1), 43-48 (2016). https://doi.org/10.1364/JOT.83.000043

Abstract:

The influence of various melanin concentrations on the endogenous fluorescence intensity of biological tissue has been experimentally studied, and the fluorescence signals have been modeled by the Monte Carlo method. The modeling is based on a four-layer optical model of the skin, using known optical parameters of skin with various melanin concentrations. The fluorescence spectra obtained by the Monte Carlo method agrees with the results of the experimental investigations.

Keywords:

optical noninvasive diagnostics, fluorescent spectroscopy, melanin, Monte Carlo method, medical and technical requirements

Acknowledgements:

This work was carried out as a basic part of a state program of the RF Ministry of Education and Science for the Federal State Budgetary Educational Institute of Higher Professional Education State University—Academic–Scientific Manufacturing Complex (No. 310).

OCIS codes: 170.6280, 170.6510

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