Method of estimating the biological age of skin by means of a fluorescence multispectral video dermatoscope

Папаян Г.В., Петрищев Н.Н., Крылова Е.В., Kang Uk, Ким С.В., Березин В.Б., Bae Soo-Jin Метод оценки биологического возраста кожи с помощью флуоресцентного мультиспектрального видеодерматоскопа // Оптический журнал. 2010. Т. 77. № 2. С. 60–67.

Papayan G.V., Petrishchev N.N., Krylova E.V., Kang Uk, Kim S.V., Berezin V.B., Bae Soo-Jin Method of estimating the biological age of skin by means of a fluorescence multispectral video dermatoscope [in Russian] // Opticheskii Zhurnal. 2010. V. 77. № 2. P. 60–67.

G. V. Papayan, N. N. Petrishchev, E. V. Krylova, Kang Uk, S. V. Kim, V. B. Berezin, and Bae Soo-Jin, "Method of estimating the biological age of skin by means of a fluorescence multispectral video dermatoscope," Journal of Optical Technology. 77(2), 126-131 (2010). https://doi.org/10.1364/JOT.77.000126

A method is proposed for evaluating age changes of the skin, based on an analysis of images obtained by means of the EcoSkin fluorescence dermatoscope. Parameters calculated by multiple regression analysis that combine information on aging at the molecular and morphological levels serve as integral markers of age changes of the skin. Measurements on sections of the skin subjected to solar action or protected from it make it possible to evaluate the photoage and bioage of the skin separately. Measurements of the corresponding parameters in seventy women with skin phototypes II and III, aged from 13 to 93 years, provided correlation coefficients of 0.83-0.87 with calendar age. When age according to the person's external appearance was taken into account, these coefficients increased to 0.92-0.94.