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ISSN: 1023-5086


ISSN: 1023-5086

Scientific and technical

Opticheskii Zhurnal

A full-text English translation of the journal is published by Optica Publishing Group under the title “Journal of Optical Technology”

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DOI: 10.17586/1023-5086-2020-87-08-21-40

УДК: 543.42, 617.713-007.64,617.713-089

Photophysical aspects of corneal cross-linking: problems and prospects (Review)

For Russian citation (Opticheskii Zhurnal):

Серебряков В.А., Бойко Э.В., Маслов В.Г., Мелихова М.В., Папаян Г.В. Фотофизические аспекты кросслинкинга роговицы. Проблемы и перспективы (обзор) // Оптический журнал. 2020. Т. 87. № 8. С. 21–40.


Serebryakov V.A., Boiko E.V., Maslov V.G., Melikhova M.V., Papayan G.V. Photophysical aspects of corneal cross-linking: problems and prospects (Review) [in Russian] // Opticheskii Zhurnal. 2020. V. 87. № 8. P. 21–40.


For citation (Journal of Optical Technology):

V. A. Serebryakov, E. V. Boiko, V. G. Maslov, M. V. Melikhova, and G. V. Papayan, "Photophysical aspects of corneal cross-linking: problems and prospects (Review)," Journal of Optical Technology. 87(8), 465-478 (2020).


Various aspects of corneal cross-linking have been considered in this review, mainly in terms of the underlying photophysical processes, including comparison with photodynamic therapy. In addition, a thorough analysis of the cross-linking processes and assessment of the problems was performed. This enabled us to recommend ways to increase the effectiveness and reduce the duration of the treatment.


cross-linking, riboflavin, collagen, proteoglycan, photodynamic therapy, cell substrate, extracellular matrix

OCIS codes: 170.4470, 170.5180, 340.7460


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